Clinical evaluation of human placental extract (placentrex) in radiation-induced oral mucositis

Kaushal, V.; Verma, K.; Manocha, S.; Hooda, H.S.; Das, B.P.

International Journal of Tissue Reactions 23(3): 105-110


To evaluate human placental extract in the treatment of radiation mucositis involving the oral/oropharyngeal region, a prospective randomized study was carried out in 120 patients with squamous cell carcinoma of the head and neck from August 1997 to March 1999. The study was conducted in patients receiving radical external radiation therapy, planned for =>60 Gy/30F/6 weeks, who developed grade 2 radiation mucositis (patchy mucositis) during radiation treatment.