Synergistic effects of geraniin and rutin in the hepatoprotective activity of phyllanthin, hypophyllanthin in Phyllanthus amarus

Aminul, I.; Mazumder, U.K.; Gupta, M.; Shibnath, G.

Journal of Interacademicia 4: 483-490


<i>Phyllanthus amarus</i>, the whole plant is well-known for its hepatoprotective effect. The major bio-active principles are phyllanthin and hypophyllanthin responsible for exerting hepatoprotection. Detailed investigation of the total extract of the whole plant indicated additionally the presence of a gallotannoid, geraniin and a flavonoid, rutin in the extract.