Biotransformation of terpenoids in mammal. I. Biotransformation of 3-carene and related compounds in rabbits
Ishida, T.; Asakawa, Y.; Okano, M.; Aratani, T.
Tetrahedron Letters 28: 2437-2440
During the course of the investigation of the detoxication mechanism of terpenoids in mammals, we have found that some monoterpene hydrocarbons and a related compound to them have been stereoselectively transformed to hydroxylated products in rabbits. We report herein the biotransformation of 1-methylcyclohexene, (+)-, (-)- and (±)-2-pinenes, (-)-2(10)-pinene and (+)-3-carene.