Cholinergic compounds. IX. Cyclohexane analogs of Deoxa muscarine and derivatives
Angeli, P.; Melchiorre, C.; Giannella, M.; Pigini, M.
Journal of Medicinal Chemistry 20(3): 398-400
The synthesis of some cyclohexane analogues of deoxamuscarine is reported. Stereochemical aspects are discussed on the basis of IR and NMR spectra. Muscarinic activity, measured on guinea pig ileum, shows a sharp drop when comparison is made with the cyclopentyl analogues.