Comparison of two antigen tests and the modified Knott's test for detection of canine heartworm at different worm burdens

Courtney, C.H.; Zeng, Q.Y.; MacKinnon, B.R.

Canine Practice 18(3): 5-7


In a retrospective study, the relative sensitivities of the two most commonly used heartworm antigen tests, DiroCHEK and CITE Semi-Quant, were compared with that of a concentration test for microfilariae (modified Knott's technique) in dogs with heartworm burdens that ranged from very low to high. Both antigen tests were significantly more sensitive than the Knott's test at all worm burdens (1-2, 2-5, 6-10, 11-20 and >20 worms).