Inherited copper toxicosis in Bedlington terriers
Robertson, H.M.; Studdert, V.P.; Reuter, R.E.
Australian Veterinary Journal 60(8): 235-238
Chronic hepatitis and increased hepatic copper concentrations, from 1,600 to 6,361 µg/g dry tissue were found in 4 related, Australian-bred Bedlington terriers. Two dogs were asymptomatic and 2 were clinically ill with signs referable to liver dysfunction. Two dogs were treated with d-penicillamine. After one year there was no improvement in the histopathological liver changes in either dog or significant lowering of hepatic copper level in one dog.