Antibody-dependent adherence of canine leukocytes to the microfilariae of the dog heartworm, Dirofilaria immitis

Buxton, B.A.; Rhodes, P.J.; Schultz, R.D.

Federation Proceedings 42(4): 852


Canine leukocytes were shown to adhere in vitro to microfilariae of Dirofilaria immitis. Polymorphonuclear (PMN) cell populations adhered to and killed microfilariae more efficiently than mononuclear (MN) cell-enriched populations. Antibody-dependent adherence of platelets to microfilariae was also observed. The neutrophil appeared to be the most important cell in the in vitro reaction.